BÜCHI Labortechnik AG Axel Semrau BISCHOFF Chromatography GmbH

Analytical Chromatography (HPLC)

BÜCHI Labortechnik AG
The Alltech® 3300 ELSD simplifies analysis of difficult compounds such as pharmaceuticals, impurities, fatty acids, or polymers. This system was developed to improve baseline stability and detection sensitivity compared to refractive index (RI), and to use ELSD in parallel with UV/Vis and MS for maximum structural and concentration information. As a result, it obtains a more accurate representation of sample mass than UV/Vis. More information

Axel Semrau
The Symbiosis™ Pico System offers all the basic advantages of online SPE (solid-phase extraction) like higher assay sensitivity, analysis of small sample injection volumes, no manual labor and lower costs of analysis while reducing method development time. It combines fully automated sample preparation with automated high-end HPLC. The system allows for parallel processing of automated sample preparation, analysis of up to 192 samples, and up to 6 selectable LC columns. More information

Axel Semrau
The Symbiosis™ Pro system offers a unique solution for integrated online SPE-LC-MS automation (XLC-MS), which combines sample extraction and LC separation in one system. XLC-MS (eXtraction Liquid Chromatography) permits direct injection of raw biological samples such as plasma, serum or urine without prior filtration, centrifugation or protein precipitation. The system allows for parallel processing of automated sample preparation and analysis of up to 9'216 samples. More information

Axel Semrau
ALIAS™ is an autosampler for HPLC and LC-MS using state-of-the-art injection technology with fast injection and wash cycles. Efficient, multi-solvent needle wash eliminates carry-over. ALIAS™ handles well plates and sample vials, either open or sealed, and provides true 4°C sample cooling. Its compact, stackable design and unrivalled performance make the ALIAS™ autosampler a perfect fit for every HPLC and UHPLC system. More information

Axel Semrau
Flow rate: 0.001 - 5.00 ml/min
Max. pressure: 1'240 bar (18'000 psi)
High pressure gradient

The SPH1240™ UHPLC ultra high pressure pump enables the use of longer columns, higher flow rates and smaller particles. The optimum combination of these parameters may vary largely with the requirements of your assay. More information

Axel Semrau
The Spark DBS Autosampler™ maintains the integrity of the sample through automation, offering more efficient, cost effective DBS sample processing. The patented FTD™ technology for sample preparation and optional online coupling to (SPE) (LC)-MS/MS allows for effortless automation of the entire workflow for DBS analysis, providing maximum sensitivity without any manual intervention. The expandable capacity from a single to a 96 card feeder gives the possibility of 384 samples for analysis in a single run. More information

Axel Semrau
Temperature range: 5 - 90 °C
Capacity: up to 6 columns simultaneously
Integrated solvent preheater
Temperature gradient programming

Chromatographic separation is very temperature dependent. Thus, the MISTRAL™ with its forced air oven, excellent temperature control and integrated solvent pre-heater helps to optimize HPLC or UHPLC assays by varying the temperature to tune selectivity, improve peak shape, reduce analysis time and column back pressure for higher solvent flow rates or smaller particles. More information

BISCHOFF Chromatography GmbH
The Bischoff HPLC columns come in a broad range of lengths, internal diameters and materials to cover a wide range of separations. If, however, no column meets the demanded separation requirements, there is also the option to fabricate according to customer specifications. Apart from filling materials of well-known manufacturers, we also offer our own substances such as ProntoSIL, HiPAK and PolyEncap. Moreover, a refill service is available with ProntoSIL as well as materials of other manufacturers. More information